If any words have become buzzwords among HNW circles in recent years, they are ‘wellness’, ‘biohacking’, ‘healthspan’ and ‘anti-ageing’. The focus has shifted from not looking older to not feeling older, from living longer to living better.
At this year’s Spear’s 500 Live conference, billionaire life-sciences investor Jim Mellon reflected on the changing attitude towards ageing: ‘The great thing about longevity is that it has really led to a shift into a different mindset where people are no longer accepting baseline health – they really want to optimise their health.’
Longevity, once the preserve of a niche group of futurists and biohackers, is increasingly becoming an organising principle for the affluent: a pursuit of greater vitality, preventative health and, ultimately, more years lived at their best. The 2026 edition of the Spear’s Longevity, Health Screening & Preventative Medicine Index tracks the businesses and innovations shaping this rapidly evolving landscape.
Explore the other rankings within the 2026 Spear’s Medical Indices:
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Advisers in year’s Index report clients’ focus shifting towards their ‘biological age’ rather than their ‘chronological age’. Where the latter counts the years since birth, the former is an estimate of how worn the body’s systems actually are, built from measurable markers, and it can differ from your chronological age by decades in either direction. Dr Angela Rai of the London General Practice says that the clinic assesses biomarkers such as insulin sensitivity or hydration and vitamin status to determine a client’s biological age. ‘These marks are influenced by our lifestyle and behaviours,’ she explains. The framing, she adds, has already changed how patients see themselves: ‘Lots of my patient will now go by their biological age.’
[See also: Skincare entrepreneur Irene Forte on longevity and life as ‘Lady Good Deal’]
Meanwhile, Lumen gathers around 2,000 data points per patient and uses BrainKey imaging to track brain volume year on year, watching for the shrinkage and white matter changes that precede dementia. Meanwhile, Primarius Clinic reads cancer risk from a blood sample using liquid biopsy, and medical practice Preventicum has build a dedicated prostate MRI service for men over 45 with a family history.
The more useful question is what the client does with the result, and here even the practitioners selling the tests sound a note of caution. ‘I have patients taking supplements that are meant to help longevity, yet they have undiagnosed diabetes,’ says Rai, who maintains that movement, sleep, nutrition and stress management remain the foundations to a long and healthy life.
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A clean (but not hefty) bill of health
‘Money doesn’t necessarily translate into longevity,’ says Jim Mellon, founder of biotech company, Juvenescence. According to the Organisation for Economic Cooperation and Development, Americans spend on average over double on healthcare than Britons, but die almost three years earlier.
King’s College London professor, Georgina Ellison-Hughes, points to a 94-year-old with the immune system of a 20-year-old built by a lifetime of exercise rather than anything purchasable, and is sceptical of the supplement market that has grown up around the field: ‘you’re not really sure what’s in those supplements.’
Proactive versus reactive
Primarius Clinic sits in between two models: reactive general practice that waits for symptoms and screening providers that see a patient once a year and call it continuity. Its position is that neither works alone, and that a client flagged as at risk of heart disease needs a monitoring schedule built around their own history rather than a letter and a follow-up in 12 months.
Lumen stages its screening by decade, testing younger patients every three years and those over 50 every 12 to 18 months. Lanserhof at The Arts Club sees most clients twice a year, more often on membership.
This shift from reactive to proactive care is changing how clients judge the doctors they keep in their circle, advisers in this year’s edition report, with success measured less by recovery than prevention.
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- Methodology
- The best preventative medicine, health screening and anti-ageing clinics: some names to know
- The best preventative medicine, health screening and anti-ageing clinics: the complete list
- Contact us
Methodology
Each year, the Spear’s Research Unit reassesses and refreshes its rankings of the leading providers in each sector by gathering data from and about the advisers and firms themselves, assessing submission forms, collating nominations, carrying out peer reviews, reviewing data from third-party sources, gathering references and recommendations, canvassing experts and conducting hundreds of interviews.
Advisers are evaluated using a proprietary scoring system that assigns different weightings to certain attributes. These scores feed directly into each new set of rankings in the Spear’s Indices. Each of these indices are published first online (according to the research calendar) and then in print. Print publication takes the form of the annual Spear’s 500 directory, which includes the top advisers in every index.
[See also: A guide to The Spear’s 500: Everything you need to know]
Each featured adviser is profiled on spears500.com. The site allows users to search the Spear’s database of more than 4,000 entities to find one (or more) to meet their specific requirements by filtering for specific attributes such as an adviser’s location, their specialist expertise and information about their client base.
The best preventative medicine, health screening and anti-ageing clinics: some names to know
Preventicum
- Focus: Early detection and prevention
London clinic Preventicum has a team of doctors and consultants who perform and analyse a series of scientifically tuned tests on their clients every 12 months, building an enviable body of data aimed at preventing illness for as long as possible.
‘We aim to have a really thorough assessment, both from a cardiometabolic and cancer-screening perspective, using a holistic approach that begins before the client even comes to us,’ says medical director Dr Asha Katwa. With all of the tests taking place in one day, Preventicum’s offering allows busy HNWs to fit a myriad of medical tests into a few hours.
‘Our clients are often very time-poor. What they value isn’t just the tests, but the interpretation, the context and the follow-through, so they leave with clarity, confidence and a sensible plan,’ Katwa tells Spear’s.
Read Preventicum’s full profile on Spears500.com
The London General Practice
- Biomarkers and anti-ageing
Founded in 2005 by Dr Paul Ettlinger and part of HCA International since 2022, The London General Practice is a private medical practice located in London’s Harley Street and which caters to UHNW and HNW individuals, families and corporations.
In addition to general medicine, the practice offers a comprehensive health screening service tailored to the unique needs of each patient. Its longevity programme, led by GP and anti-ageing specialist Dr Angela Rai, estimates how fast a patient is ageing rather than how long they have been alive, reading chemical tags on DNA that shift with diet, sleep and exercise.
The resulting figure can be moved, she explains: ‘These marks are influenced by our lifestyle and our behaviours.’ She is unsentimental, however, about patients who chase longevity while overall health goes unattended. ‘I have patients taking supplements that are meant to help longevity, yet they have undiagnosed diabetes.’
Read The London General Practice’s full profile on Spears500.com
Lumen
- Focus: Advanced health assessments
The thorough programme of tests carried out at the Lumen clinic in Harley Street is designed to detect problems that might indicate future risks, such as heart disease or the very early stages of common cancers, so they can be treated as non-invasively as possible.
Dr Garry Savin, an experienced GP, leads the team of dedicated nurses, cardiologists, radiographers and MRI scanning technicians at Lumen who perform the wide range of assessments on offer. He describes the practice as the ‘Rolls-Royce’ of health screening.
The clinic also uses a technology called BrainKey, Savin tells Spear’s. ‘Basically, we can measure each individual part of the brain with 3D biometric analysis and plot data over time to see if the brain is shrinking too fast … that can be an indication of early neurodegenerative diseases.’
Read Lumen’s full profile on Spears500.com
Primarius Clinic
- Focus: Preventative Care
Primarius Clinic, located at the Royal Brompton private clinic in Marylebone, provides clients with full-body health assessments and diagnostic tests, focusing on ‘meaningful and precision preventative medicine’.
‘We’ve created a very high-end, bespoke type of health check for people,’ partner and practice GP Dr Robby Bajaj tells Spear’s. ‘We’re trying to prevent people who don’t know they’ve got an issue from developing a significant health condition.’
The suite of tests offered to an individual is determined by their symptoms, family history and demographic indicators. Primarius also provides private GP services for those interested in care between regular health checks. ‘We test in intervals, but it’s not a conveyor belt where we do one annual health check and then say, “See you next year.”’
Read Primarius Clinic’s full profile on Spears500.com
Lanserhof at the Arts Club
- Focus: Health and fitness optimisation
Lanserhof at The Arts Club is one of London’s most exclusive private wellness clinics, focused on fitness, diagnostics and biomechanics. Each member has access to cutting-edge technology and their own bespoke wellness plan.
The clinic advertises ‘targeted precision optimisation’ tests for patients using technology such as MRIs, and tools and treatments such as vitamin injections, nutrition plans and sleep analysis. All in an effort to ‘move the needle for people that might have chronic diseases in their family or are chronically injured’.
Members’ medical, fitness, performance and restoration needs are a priority, and those interested in an active lifestyle, whether it be recreationally or as a professional athlete, can access the facility’s team of physiotherapists, biomechanics experts and other specialists to optimise their performance and achieve their fitness goals.
Read Lanserhof at the Arts Club’s full profile on Spears500.com
The best preventative medicine, health screening and anti-ageing clinics: the complete list
Click on the individual names to be directed to more detailed profiles of each adviser on The Spear’s 500 website. The table is ordered by ranking and then alphabetically by surname.
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